What is Dupuytren's Disease?
Fast Facts About Dupuytren's Disease
- It presents as a thickening of the skin of the palm of the hand.
- It's hereditary (Autosomal dominant), especially of "Viking heritage."
- Most common among middle age (40-60) individuals.
- More common in men (Male: Female ratio is 7 to 1.)
- Typically presents with contracture of the metacarpophalangeal joint (knuckle joint) and proximal interphalangeal joint (one of the joints of the fingers.)
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Dupuytren's Contracture of the Ring Finger (Photograph Courtesy of Frank C. Muller, Wikimedia Commons) |
Associated Diseases
- Epilepsy (most common)
- Alcoholism
- Diabetes Mellitus
- Smoking
- NOT related to manual work.
When would Treatment be Needed for Dupuytren's Disease?
- When there's contracture of the metacarpophalangeal joint or MP joint of >30 degrees
- When there's contracture of the proximal phalangeal joint or PIP joint
- Nodules alone does not need surgery.
What kind of Treatments Available?
- Collagenase injections
- Needle aponeurotomy or percutaneous Dupuytren's Contracture release in selected patients.
- Selective or Extensive Palmar fasciectomy and Dupuytren's contracture release.
I recommend asking one of your Houston Plastic Surgeons about your Dupuytren's disease if it requires treatment or not.
Emmanuel De La Cruz M.D.
Emmanuel De La Cruz M.D.
Reference:
Badalamente MA, Hurst LC: Enzyme injection as non-surgical treatment of Dupuytren’s
Disease. J Hand Surg 25A: 629-636, 2000.
Disease. J Hand Surg 25A: 629-636, 2000.
Burge P, Hoy G, Regan P, Milne R: Smoking, alcohol and the risk of Dupuytren’s contracture.
J Bone and Joint Surg 79B: 206-210, 1997.
J Bone and Joint Surg 79B: 206-210, 1997.
Chammas M, Bousquet P, Renard E, Poirier J- L, Jaffiol C, Allieu Y: Dupuytren’s Disease,
Carpal Tunnel Syndrome, Trigger Finger, and Diabetes Mellitus. J Hand Surg 20A: 109-114,
1995.
Carpal Tunnel Syndrome, Trigger Finger, and Diabetes Mellitus. J Hand Surg 20A: 109-114,
1995.
Critchley EMR, Valcil SD, Hayward HW, Owan VMH: Dupuytren’s disease in epilepsy. J
Neurol Neurosurg Psych 39: 498, 1976.
Neurol Neurosurg Psych 39: 498, 1976.
Ling RSM: The genetic factor in Dupuytren’s disease. J Bone and Joint Surg 45B: 709, 1963.
Starkweather ICD, Lattuga S, Hurst LC, et al. Collagenase in the treatment of Dupuytren’s
disease: an in vitro stud y. J Hand Surg 21A: 490-495, 1996.
disease: an in vitro stud y. J Hand Surg 21A: 490-495, 1996.